I did suffer from serious mouse and keyboard hangups after installing the nvidia drivers. It occurred frequently, within 10 minutes after booting.
I have some issues with opening files that were created using more recent versions of the Software I am using. As an example, none of the LMMS compositions I created on my ArchLinux running LMMS v 1.1.3 can be opened in LMMS 1.0.0.