python-btchip

Python library to communicate with BTChip dongle
  https://github.com/LedgerHQ/btchip-python
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HW-1 is a secure tiny USB smart card based hardware wallet, keeping your bitcoin based crypto-currency assets safe. The built-in smart card holds your private keys, and signs transactions after you confirm them. Cheap, fun, easy to use, yet offering a rich API for developers, HW-1 makes crypto coins security convenient.

For more info, visit: https://hardwarewallet.com/