python3-gffutils

Work with GFF and GTF files in a flexible database framework
  https://daler.github.io/gffutils
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A Python package for working with and manipulating the GFF and GTF format files typically used for genomic annotations. Files are loaded into a sqlite3 database, allowing much more complex manipulation of hierarchical features (e.g., genes, transcripts, and exons) than is possible with plain-text methods alone.