Simple and fast command-line framework to process sequencing data from a Hi-C experiment.

Process pair-end sequence alignments and perform the following operations:

- Detect ligation junctions (a.k.a. Hi-C pairs) in aligned paired-end sequences of Hi-C DNA molecules - Sort .pairs files for downstream analyses - Detect, tag and remove PCR/optical duplicates - Generate extensive statistics of Hi-C datasets - Select Hi-C pairs given flexibly defined criteria - Restore .sam alignments from Hi-C pairs