r-bioc-beachmat

I/O for several formats storing matrix data
  https://bioconductor.org/packages/beachmat/
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Provides a consistent C++ class interface for reading from and writing data to a variety of commonly used matrix types. Ordinary matrices and several sparse/dense Matrix classes are directly supported, third-party S4 classes may be supported by external linkage, while all other matrices are handled by DelayedArray block processing.