Alakazam is part of the Immcantation analysis framework for Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) and provides a set of tools to investigate lymphocyte receptor clonal lineages, diversity, gene usage, and other repertoire level properties, with a focus on high-throughput immunoglobulin (Ig) sequencing.

Alakazam serves five main purposes: * Providing core functionality for other R packages in the Immcantation framework. This includes common tasks such as file I/O, basic DNA sequence manipulation, and interacting with V(D)J segment and gene annotations. * Providing an R interface for interacting with the output of the pRESTO and Change-O tool suites. * Performing lineage reconstruction on clonal populations of Ig sequences and analyzing the topology of the resultant lineage trees. * Performing clonal abundance and diversity analysis on lymphocyte repertoires. * Performing physicochemical property analyses of lymphocyte receptor sequences.