yubikey-manager

Python library and command line tool for configuring a YubiKey
  https://developers.yubico.com/yubikey-manager/
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YubiKey Manager (ykman) is a command line tool for configuring a YubiKey over all transports. It is capable of reading out device information as well as configuring several aspects of a YubiKey, including enabling or disabling connection transports and programming various types of credentials.

YubiKey is a specific series of personal Hardware Security Modules, meant to protect private keys tied to its users (for 2nd factor authentication, use with OpenPGP, ...).